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1

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Girardini, Miriam, Maniaci, Chiara, Hughes, Scott J., Testa, Andrea, Ciulli, Alessio

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.42 MB

english, 2019

2

Structural basis of PROTAC cooperative recognition for selective protein degradation

Gadd, Morgan S, Testa, Andrea, Lucas, Xavier, Chan, Kwok-Ho, Chen, Wenzhang, Lamont, Douglas J, Zengerle, Michael, Ciulli, Alessio

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

3

Impact of target warhead and linkage vector on inducing protein degradation: comparison of Bromodomain and Extra-Terminal (BET) degraders derived from triazolodiazepine (JQ1) and tetrahydroquinoline (I-BET726) BET inhibitor scaffolds

Chan, Kwok-Ho, Zengerle, Michael, Testa, Andrea, Ciulli, Alessio

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

4

Optimization of a “Bump-and-Hole” Approach to Allele-Selective BET Bromodomain Inhibition

Runcie, Andrew, Zengerle, Michael, Chan, Kwok-Ho, Testa, Andrea, van Beurden, Lars, Baud, Matthias, Epemolu, Ola, Ellis, Lucy, Read, Kevin, Coulthard, Victoria, Brien, Alex, Ciulli, Alessio

Journal:

Chemical Science

Year:

2018

Language:

english

File:

PDF, 3.96 MB

english, 2018

5

Experimental investigation on wear map evolution of ceramic-on-UHMWPE hip prosthesis

Mattei, Lorenza, Di Puccio, Francesca, Ciulli, Enrico, Pauschitz, Andreas

Journal:

Tribology International

Year:

2019

Language:

english

File:

PDF, 2.22 MB

english, 2019

6

Novel Repair for Late Posttraumatic Aortic Valve Injury and Root Pseudoaneurysm

Andrea Venturini, Raimondo Ascione, Franco Ciulli, Elvio Polesel, Roberto Moretti, Gianni D. Angelini, Claudio Zussa

Journal:

The Annals of Thoracic Surgery

Year:

2006

Language:

english

File:

PDF, 208 KB

english, 2006

7

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

Inge Van Molle, Andreas Thomann, Dennis L. Buckley, Ernest C. So, Steffen Lang, Craig M. Crews, Alessio Ciulli

Journal:

Chemistry & Biology

Year:

2012

Language:

english

File:

PDF, 970 KB

english, 2012

8

Transsternal approach to closure of bronchopleural fistulas after pneumonectomy. A fifteen cases report

Beltrami, Vanni, Angelici, Alberto, Bertagni, Alessandro, Bezzi, Marcello, Ciulli, Andrea, Forte, Angelo, Gallinaro, Luca, Illuminati, Giulio, Montesano, Giuseppe, Prece, Valentina

Journal:

Year:

2000

Language:

english

File:

PDF, 272 KB

english, 2000

9

[IEEE 2012 14th International Conference on Transparent Optical Networks (ICTON) - Coventry, United Kingdom (2012.07.2-2012.07.5)] 2012 14th International Conference on Transparent Optical Networks (ICTON) - Research trends on ICT convergence from the CaON cluster

Figuerola, Sergi, Simeonidou, Dimitra, Palacios, Juan F., Di Giglio, Andrea, Ciulli, N., Garcia, J. A., Nejabati, R., Masip, X., Munoz, R., Landi, G., Yannuzzi, M., Casellas, R.

Year:

2012

Language:

english

File:

PDF, 92 KB

english, 2012

10

[IEEE 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Milan (2015.8.25-2015.8.29)] 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Multimodal MRI classification in vascular mild cognitive impairment

Diciotti, Stefano, Ciulli, Stefano, Ginestroni, Andrea, Salvadori, Emilia, Poggesi, Anna, Pantoni, Leonardo, Inzitari, Domenico, Mascalchi, Mario, Toschi, Nicola

Year:

2015

Language:

english

File:

PDF, 656 KB

english, 2015

11

Low MT ratio in hippocampus of amnestic MCI patients who will progress to AD

Mascalchi, Mario, Bessi, Valentina, Ginestroni, Andrea, Toschi, Nicola, Ciulli, Stefano, Padiglioni, Sonia, Bracco, Laura, Diciotti, Stefano

Journal:

Journal of Neurology

Year:

2016

Language:

english

File:

PDF, 388 KB

english, 2016

12

Diffusion Tensor Imaging to Map Brain Microstructural Changes in CADASIL

Mascalchi, Mario, Pantoni, Leonardo, Giannelli, Marco, Valenti, Raffaella, Bianchi, Andrea, Pracucci, Giovanni, Orsolini, Stefano, Ciulli, Stefano, Tessa, Carlo, Poggesi, Anna, Pescini, Francesca, Inz

Journal:

Journal of Neuroimaging

Year:

2016

Language:

english

File:

PDF, 988 KB

english, 2016

13

Resting state fMRI regional homogeneity correlates with cognition measures in subcortical vascular cognitive impairment

Diciotti, Stefano, Orsolini, Stefano, Salvadori, Emilia, Giorgio, Antonio, Toschi, Nicola, Ciulli, Stefano, Ginestroni, Andrea, Poggesi, Anna, De Stefano, Nicola, Pantoni, Leonardo, Inzitari, Domenico

Journal:

Journal of the Neurological Sciences

Year:

2017

Language:

english

File:

PDF, 390 KB

english, 2017

14

Lower medulla hypoplasia in Friedreich ataxia: MR Imaging confirmation 140 years later

Mascalchi, Mario, Bianchi, Andrea, Ciulli, Stefano, Ginestroni, Andrea, Aiello, Marco, Dotti, Maria Teresa, Salvi, Fabrizio, Nicolai, Emanuele, Soricelli, Andrea, Diciotti, Stefano

Journal:

Journal of Neurology

Year:

2017

Language:

english

File:

PDF, 542 KB

english, 2017

15

Mind the metal: a fragment library-derived zinc impurity binds the E2 ubiquitin-conjugating enzyme Ube2T and induces structural rearrangements

Morreale, Francesca E., TESTA, ANDREA, Chaugule, Viduth K., Bortoluzzi, Alessio, Ciulli, Alessio, Walden, Helen

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

16

Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

Maniaci, Chiara, Hughes, Scott J., Testa, Andrea, Chen, Wenzhang, Lamont, Douglas J., Rocha, Sonia, Alessi, Dario R., Romeo, Roberto, Ciulli, Alessio

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 3.00 MB

english, 2017

17

DTI-derived indexes of brain WM correlate with cognitive performance in vascular MCI and small-vessel disease. A TBSS study

Mascalchi, Mario, Salvadori, Emilia, Toschi, Nicola, Giannelli, Marco, Orsolini, Stefano, Ciulli, Stefano, Ginestroni, Andrea, Poggesi, Anna, Giorgio, Antonio, Lorenzini, Francesca, Pasi, Marco, De St

Journal:

Brain Imaging and Behavior

Year:

2018

Language:

english

File:

PDF, 2.18 MB

english, 2018

18

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

TESTA, ANDREA, Lucas, Xavier, Castro, Guilherme, Chan, Kwok-Ho, Wright, Jane, Runcie, Andrew, Gadd, Morgan, Harrison, William T A, Ko, Eun-Jung, Fletcher, Dan, Ciulli, Alessio

Journal:

Journal of the American Chemical Society

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

19

Structural Complexity of the Cerebellum and Cerebral Cortex is Reduced in Spinocerebellar Ataxia Type 2

Marzi, Chiara, Ciulli, Stefano, Giannelli, Marco, Ginestroni, Andrea, Tessa, Carlo, Mascalchi, Mario, Diciotti, Stefano

Journal:

Journal of Neuroimaging

Year:

2018

Language:

english

File:

PDF, 426 KB

english, 2018

20

Histogram analysis of DTI-derived indices reveals pontocerebellar degeneration and its progression in SCA2

Mascalchi, Mario, Marzi, Chiara, Giannelli, Marco, Ciulli, Stefano, Bianchi, Andrea, Ginestroni, Andrea, Tessa, Carlo, Nicolai, Emanuele, Aiello, Marco, Salvatore, Elena, Soricelli, Andrea, Diciotti,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

21

Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of BRD9 and BRD7

Zoppi, Vittoria, Hughes, Scott J, Maniaci, Chiara, TESTA, ANDREA, Gmaschitz, Teresa, Wieshofer, Corinna, Koegl, Manfred, Riching, Kristin, Daniels, Danette L., Spallarossa, Andrea, Ciulli, Alessio

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 7.27 MB

english, 2018

22

New molecular and therapeutic insights into canine diffuse large B cell lymphoma elucidates the role of the dog as a model for human disease

Aresu, Luca, Ferraresso, Serena, Marconato, Laura, Cascione, Luciano, Napoli, Sara, Gaudio, Eugenio, Kwee, Ivo, Tarantelli, Chiara, Testa, Andrea, Maniaci, Chiara, Ciulli, Alessio, Hillmann, Petra, Bo

Journal:

Year:

2018

Language:

english

File:

PDF, 1.39 MB

english, 2018

23

Vector boson scattering: Recent experimental and theory developments

Alessandro, Ballestrero, Riccardo, Bellan, Benedikt, Biedermann, Carsten, Bittrich, Ilaria, Brivio, Andrea, Cardini, Guillelmo, Gomez-Ceballos, Claude, Charlot, Vitaliano, Ciulli, Roberto, Covarelli,

Journal:

Reviews in Physics

Year:

2018

File:

PDF, 3.02 MB

2018

24

Rapid and reversible knockdown of endogenously tagged endosomal proteins via an optimized HaloPROTAC degrader.

Tovell, Hannah, TESTA, ANDREA, Maniaci, Chiara, Zhou, Houjiang, Prescott, Alan R, Macartney, Thomas, Ciulli, Alessio, Alessi, Dario R

Journal:

ACS Chemical Biology

Year:

2019

File:

PDF, 1.86 MB

2019

25

Correction to “3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation”

Testa, Andrea, Lucas, Xavier, Castro, Guilherme V., Chan, Kwok-Ho, Wright, Jane E., Runcie, Andrew C., Gadd, Morgan S., Harrison, William T. A., Ko, Eun-Jung, Fletcher, Daniel, Ciulli, Alessio

Journal:

Journal of the American Chemical Society

Year:

2019

Language:

english

File:

PDF, 865 KB

english, 2019

26

Correction to “3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation”

Testa, Andrea, Lucas, Xavier, Castro, Guilherme V., Chan, Kwok-Ho, Wright, Jane E., Runcie, Andrew C., Gadd, Morgan S., Harrison, William T. A., Ko, Eun-Jung, Fletcher, Daniel, Ciulli, Alessio

Journal:

Journal of the American Chemical Society

Year:

2019

File:

PDF, 865 KB

2019

27

Design and characterization of SGK3-PROTAC1, an isoform specific SGK3 kinase PROTAC degrader

Tovell, Hannah, Testa, Andrea, Zhou, Houjiang, Shpiro, Natalia, Crafter, Claire, Ciulli, Alessio, Alessi, Dario R

Journal:

ACS Chemical Biology

Year:

2019

Language:

english

File:

PDF, 1.48 MB

english, 2019

28

Handedness Side and Magnetization Transfer Ratio in the Primary Sensorimotor Cortex Central Sulcus

Mascalchi, Mario, Ciulli, Stefano, Bianchi, Andrea, Marzi, Chiara, Orsolini, Stefano, Gavazzi, Gioele, Aiello, Marco, Nicolai, Emanuele, Soricelli, Andrea, Giannelli, Marco, Diciotti, Stefano

Journal:

BioMed Research International

Year:

2019

Language:

english

File:

PDF, 2.24 MB

english, 2019

29

Structure-Based Design of a Macrocyclic PROTAC

Ciulli, Alessio, Testa, Andrea, Hughes, Scott J., Lucas, Xavier, Wright, Jane E.

Journal:

Angewandte Chemie International Edition

Year:

2019

Language:

english

File:

PDF, 4.36 MB

english, 2019

30

Structure‐Based Design of a Macrocyclic PROTAC

Ciulli, Alessio, Testa, Andrea, Hughes, Scott J., Lucas, Xavier, Wright, Jane E.

Journal:

Angewandte Chemie

Year:

2019

Language:

english

File:

PDF, 4.36 MB

english, 2019

31

Treatment of hepatocarcinoma beyond the milan criteria. A weighted comparative study of surgical resection versus chemoembolization

Famularo, Simone, Di Sandro, Stefano, Giani, Alessandro, Bernasconi, Davide P., Lauterio, Andrea, Ciulli, Cristina, Rampoldi, Antonio G., Corso, Rocco, De Carlis, Riccardo, Romano, Fabrizio, Braga, Ma

Journal:

Year:

2020

Language:

english

File:

PDF, 889 KB

english, 2020

32

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

Simpson, Luke M., Macartney, Thomas J., Nardin, Alice, Fulcher, Luke J., RÃ¶th, Sascha, Testa, Andrea, Maniaci, Chiara, Ciulli, Alessio, Ganley, Ian G., Sapkota, Gopal P.

Journal:

Cell Chemical Biology

Year:

2020

File:

PDF, 4.76 MB

2020

33

Corrigendum to âHandedness Side and Magnetization Transfer Ratio in the Primary Sensorimotor Cortex Central Sulcusâ

Mascalchi, Mario, Ciulli, Stefano, Bianchi, Andrea, Marzi, Chiara, Orsolini, Stefano, Gavazzi, Gioele, Aiello, Marco, Nicolai, Emanuele, Soricelli, Andrea, Giannelli, Marco, Diciotti, Stefano

Journal:

BioMed Research International

Year:

2020

File:

PDF, 387 KB

2020

34

Understanding and improving the membrane permeability of VH032-based PROTACs

Klein, Victoria G, Townsend, Chad E., Testa, Andrea, Zengerle, Michael, Maniaci, Chiara, Hughes, Scott J, Chan, Kwok-Ho, Ciulli, Alessio, Lokey, R. Scott

Journal:

ACS Medicinal Chemistry Letters

Year:

2020

File:

PDF, 1.17 MB

2020

35

Stereoselective synthesis of allele-specific BET inhibitors

Bond, Adam G., Testa, Andrea, Ciulli, Alessio

Journal:

Organic & Biomolecular Chemistry

Year:

2020

File:

PDF, 1.46 MB

2020

36

Effects of increasing dietary level of organic acids and nature-identical compounds on growth, intestinal cytokine gene expression and gut microbiota of rainbow trout (Oncorhynchus mykiss) reared at normal and high temperature

Pelusio, Nicole Francesca, Rossi, Barbara, Parma, Luca, Volpe, Enrico, Ciulli, Sara, Piva, Andrea, D'Amico, Federica, Scicchitano, Daniel, Candela, Marco, Gatta, Pier Paolo, Bonaldo, Alessio, Grilli,

Journal:

Fish & Shellfish Immunology

Year:

2020

File:

PDF, 2.73 MB

2020

37

Multifactorial Causes of Chronic Mortality in Juvenile Sturgeon (Huso huso)

Ciulli, Sara, Volpe, Enrico, Sirri, Rubina, Tura, Giorgia, Errani, Francesca, Zamperin, Gianpiero, Toffan, Anna, Silvi, Marina, Renzi, Andrea, Abbadi, Miriam, Biasini, Lorena, Pretto, Tobia, Emmanuele

Journal:

Year:

2020

File:

PDF, 10.04 MB

2020

38

Effects of dietary organic acids and nature identical compounds on growth, immune parameters and gut microbiota of European sea bass

Busti, Serena, Rossi, Barbara, Volpe, Enrico, Ciulli, Sara, Piva, Andrea, DâAmico, Federica, Soverini, Matteo, Candela, Marco, Gatta, Pier Paolo, Bonaldo, Alessio, Grilli, Ester, Parma, Luca

Journal:

Scientific Reports

Year:

2020

File:

PDF, 2.78 MB

2020

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